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increasing prevalence of rifampicin-resistant mycobacterium

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increasing prevalence of rifampicin-resistant mycobacterium

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increasing prevalence of rifampicin-resistant mycobacterium

Prevalence of Mycobacterium tuberculosis and Its Rifampicin Resistance The prevalence of pulmonary tuberculosis among children was (%), and two (%) of them were rifampicin-resistant. The prevalence of pulmonary tuberculosis among different age categories of children showed (%), (%), and (%) among the age groups ...

Dec , &#;&#;Prevalence of rifampicin-resistant Mycobacterium tuberculosis among human-immunodeficiency-virus-seropositive patients ... increasing the risk of reactivation of latent TB infection, as well as increasing the chance of TB ... Hom et al. reported a high prevalence of rifampicin resistance and MDR-TB, with a prevalence of % in patients ...

Mar , &#;&#;Huo F, Luo J, Shi J, Zong Z, Jing W, Dong W, Dong L, Ma Y, Liang Q, Shang Y, Huang H, Pang Y. . A -year comparative analysis shows that increasing prevalence of rifampin-resistant Mycobacterium tuberculosis in China is associated with the transmission of strains harboring compensatory mutations. Antimicrob Agents Chemother :e.

rifampicin resistance, molecular beacons is used to probe the rifampicin resistance determining region of rpoB gene is []. Therefore, identification of resistance to rifampicin can be accomplished within two hours. The aim of this study is to determine the prevalence of rifampicin resistant TB in our locale using the automated

Jun , &#;&#; Prevalence of drug resistance-conferring mutations associated with isoniazid and rifampicin resistant Mycobacterium tuberculosis in Ethiopia: A systematic review and meta-analysis Melese Abate Retaa, b*, Birhan Alemnewa, Biruk Beletew Abatec a Department of Medical Laboratory Science, College of Health Sciences, Woldia University, Woldia, Ethiopia

Rifampicin-resistant Mycobacterium tuberculosis by GeneXpert MTB/RIF and Associated Factors Among Presumptive Pulmonary Tuberculosis Patients in Nepal. Download. Related Papers. Trend Analysis And Seasonality Of Tuberculosis Among Patients At The Hiwot Fana Specialized University Hospital, Eastern Ethiopia: A Retrospective Study ...

May , &#;&#;Results. Ninety seven M.tuberculosis isolates were characterized, of which were MDR, seven rifampicin-resistant, isoniazid-mono-resistant, and susceptible to rifampicin and isoniazid. Sequence analysis of the rpoB rifampicin-resistance determining region (rpoB/RRDR) revealed mutations in six codons: , , , , , and , of which SerLeu was the

level kanamycin resistance in addition to confirmation of M. tuberculosis). Data analysis was carried out using chi-square test to analyze the difference in mutations detected. In total, the prevalence for the resistance to first and second-line TB drugs was % (/). Rifampicin resistant strain had the rpoB mutation SL; isoniazid

Increasing proportions of rifampicin mono-resistance resistance (RMR) have recently been reported from South Africa and other countries. Objective: This laboratory based study was conducted at NHLS TB Laboratory, Durban, which is the reference laboratory for culture and

The prevalence of drug resistance detected during the period is summarized in the Table. Among previously untreated cases, the preva-lence of resistance to isoniazid, rifampicin, ethambutol, and strepto-mycin was %, %, %, and %, respectively, while prevalence of multidrug resistance (resistance to

Oct , &#;&#;Multidrug-resistant tuberculosis (MDR-TB) has become a major threat to the control of tuberculosis globally. Uganda is among the countries with a relatively high prevalence of tuberculosis despite significant control efforts. In this study, the drug resistance of Mycobacterium tuberculosis to rifampicin (RIF) and isoniazid (INH) was investigated among patients diagnosed with pulmonary ...

Jan , &#;&#;Therefore, few studies have been published demonstrating the prevalence of rifampicin-resistant, isoniazid-susceptible M. tuberculosis [, , ]. Evidence from South Africa suggests that rates of RR-TB may be higher than previously estimated and increasing.

Research Article Rifampicin-monoresistant Mycobacterium tuberculosis among the patients visiting Chest Clinic, State Specialist Hospital, Akure, Nigeria Lateef A. Bello, Mujeeb O. Shittu*, Bashirat T. Shittu, Adeolu S. Oluremi, Oluwagbenga N. Akinnuroju, Saheed A. Adekola Department of Medical Laboratory Services, Outreach Women and Children Hospital, Festac Town, Lagos State, Nigeria ...

Rifampicin (RIF) resistance was %, % and % respectively from to ; but the trend was not statistically significant ( = ; p = ). Conclusion: The study showed that despite a decrease in the prevalence of tuberculosis infection there was an increase in rifampicin resistance from % to % between and .

Sep , &#;&#;Early detection of drug-resistant Mycobacterium tuberculosis should be given enough attention to strengthen the management of tuberculosis cases and improve direct observation therapy short-course and eventually minimize the spread of rifampicin-resistant tuberculosis strain in

Muthaiah M, Shivekar SS, Kapalamurthy VRC, Alagappan C, Sakkaravarthy A, et al. Prevalence of mutations in genes associated with rifampicin and isoniazid resistance in Mycobacterium tuberculosis clinical isolates. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases. ; : .

Apr , &#;&#;Rapid detection of rifampicin resistance is essential for early management and prevention of transmission of multidrug-resistant tuberculosis (MDR-TB). We studied the prevalence of rifampicin resistance of Mycobacterium tuberculosis (MTB) among presumptive TB patients in Addis Ababa, Ethiopia. A retrospective cross sectional study was conducted in three referral hospitals and

With the high prevalence of TB and the high rifampicin resistance (MDR-TB) in Benue State, policy makers and government should increase budgetary allocations for TB control and prevention through sourcing or appealing to international organizations for finance.

Apr , &#;&#;From this prevalence, % was shared by Rifampcin mono-resistant Tuberculosis. Conclusion: Based on our study finding, The overall prevalence of pulmonary tuberculosis was %. From these, % was account for Rifampicin Mono-Resistance Mycobacterium tuberculosis among study subject. Most of the affected study subjects were productive age group.

Aug , &#;&#;Molecular Detection of Rifampicin and Isoniazid Resistance and Characterization of Mutations in Mycobacterium tuberculosis Complex using Line Probe Assay Namratha W. Nandihal* and M.K. Anand Department of Microbiology, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India *Corresponding author A B S T R A C T resistant tuberculosis.

Introduction: Tuberculosis (TB) is a major health problem, mainly in resource-limited settings. The aim of this study was to determine the prevalence of TB and rifampicin-resistant Mycobacterium ...

May , &#;&#;Rifampicin resistance, Mycobacterium tuberculosis, risk factors, prevalence of TB, Hawassa, Ethiopia Date received: May ; accepted: August Hawassa Health Science College, Hawassa, Ethiopia

Jan , &#;&#;The increasing incidence of multidrug-resistant tuberculosis (MDRTB), defined as resistance to at least rifampin and isoniazid, is a notable global health problem ().The rapid identification of patients with MDRTB enables early institution of appropriate treatment, which is associated with improved survival (,), and infection control procedures to minimize risk of transmission ().

Prevalence; MDR-Mycobacterium tuberculosis ... worldwide surveys documents drug resistant TB . as a rapidly increasing problem hence requiring a rather complicated ... resistance to Rifampicin ...

However, genetic probes which detect drug resistance to rifampicin with >% accuracy are very suggestive of MDR-TB; <% of rifampicin resistance is monoresistant, and so rifampicin resistance is a marker for MDR-TB in >% of cases []. Because of its increasing prevalence MDR-TB is now subdivided into basic MDR-TB, with resistance only to

Prevalence of drug-resistant pulmonary tuberculosis in India: systematic review and meta-analysis ... The alarming increase in the trend of anti-TB drug resistance in India warrants the need for a ... rifampicin-resistant (RR-TB) cases in [].

Citation: Kateregga NJ, Atuheire C, Ntambi S, Ocaka D, Ndukui GJ and Wampande E. Prevalence of Multidrug Resistant . Mycobacterium tuberculosis. and

Apr , &#;&#;Al-Mutairi, N.M., Ahmad, S. & Mokaddas, E. Increasing prevalence of resistance to second-line drugs among multidrug-resistant Mycobacterium tuberculosis isolates in Kuwait. Sci Rep , ( ...

In this work, we conducted bacterial population profile studies to assess trends of rifampin (RIF) resistance of Mycobacterium tuberculosis isolates collected across China from to . Totals of and randomly selected M. tuberculosis isolates from and , respectively, were analyzed. The rates of RIF resistance (%), isoniazid resistance (%), and levofloxacin ...

Jun , &#;&#;Highlights Tuberculosis(TB), particularly drug resistance TB (DR-TB) continues to be a major public health threat globally. Herein, we used a systematic literature search on reliable electronic databases, and perform a meta-analysis to assess the prevalence of the gene mutations associated with rifampicin (RIF) and isoniazid (INH) resistant Mtb in Ethiopia.

analysis of Rifampicin resistance by Xpert MTB/RIF assay. Out of the (%) culture positive samples, % of pulmonary samples and % of extra-pulmonary samples were Rifampicin resistant. The prevalence of Rifampicin resistant TB in our study is high and the possible reasons

Oct , &#;&#;Observations of increasing resistance in patients treated for leprosy have been reported in Southeast Asia, notably in Vietnam. [] Although drug resistance is an ongoing concern, it is difficult ...

Mar , &#;&#;INTRODUCTION. Drug-resistant Mycobacterium tuberculosis, especially strains causing multidrug-resistant tuberculosis (MDR-TB), is defined as M. tuberculosis with resistance to at least rifampin (RIF) and isoniazid (INH). Despite decreases in global TB incidence and mortality, the emergence of MDR-TB represents a major challenge that is impeding progress toward TB elimination

Purpose: To analyze prevalence of mutations in genes associated with rifampicin and isoniazid resistance in Mycobacterium tuberculosis clinical isolates from patients with possible MDR TB of ...

Oct , &#;&#;Multidrug-resistant tuberculosis (MDR-TB) is a form of TB caused by bacteria that do not respond to isoniazid and rifampicin, the most effective first-line anti-TB drugs. MDR-TB is treatable and curable by using second-line drugs.

The "successful" Russian clone B/W of Mycobacterium tuberculosis Beijing is well-known for its capacity to develop antibiotic resistance. During treatment, resistant mutants can occur that have inheritable resistance to specific antibiotics. Next to mutations, M. tuberculosis has several mechani

Multidrug Resistance, Mycobacterium, Prevalence, Rifampicin Resistance, Tuberculosis Share and Cite: Chala, B. and Usmael, A. () Prevalence of Multidrug Resistant Mycobacterium tuberculosis among Tuberculosis Patients Admitted to Adama Hospital Medical College, Adama, Ethiopia: A Retrospective Study.

multi-drug-resistant (MDR) and extensively drug resistant (XDR) tuberculosis can be treated if identified accurately with early effective diagnostic approach []. Thus, an increasing global incidence of drug-resistant mycobacterium tuberculosis infection has promoted the critical

Aug , &#;&#;The objective of the present study is to find the prevalence of Mycobacterium tuberculosis from respiratory samples like sputum, BAL and pleural fluid, compare conventional LJ culture with rapid culture method i.e Mycobacterium growth indicator tube (MGIT) and to determine the pattern of drug resistance by automated methods i.e Gene Xpert.. Respiratory samples were collected in

Aug , &#;&#;Background: Mycobacterium tuberculosis (MTB) remains a major public health problem worldwide, and emergence of drug-resistant TB has become a significant obstacle to effective TB control. However, the rate of MTB and rifampicin resistant-MTB (RR-MTB) in the Nepalese setting has not been studied extensively. Therefore, the present study aims to ...

Apr , &#;&#;However, the prevalence of mutations conferring resistance to FQs or SLIDs (pre-XDR-TB) was significantly higher during to compared to to ( of versus of , P = ) strongly suggesting that the prevalence of these mutations is increasing in Kuwait. The prevalence of resistance to FQs has also increased among MDR-TB ...

Feb , &#;&#;Table also showed that % of new patients and % of retreatment patients have resistance to isoniazid (monodrug resistance), whereas it was % and % for rifampicin monodrug resistance.. . MDR-TB Prevalence in Rifampicin-Resistant TB Patients. Among the RR-TB cases, (%) were also resistant to isoniazid, and therefore classified as MDR-TB.

Apr , &#;&#;Rifampicin resistant TB was % (/) in all TB confirmed cases and % (/) in paediatric TB patients. The prevalence of rifampicin resistant TB among new and previously treated was and %, respectively. Sex (being female) and previous TB treatment were significantly associated with rifampicin resistant TB. Conclusions

Jul , &#;&#;Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), affects ~ million people annually .Despite a recent reduction in TB incidence, increasing drug resistance is

Prevalence of rifampicin resistant mycobacterium tuberculosis and associated factors among presumptive tuberculosis patients in eastern Uttar Pradesh: a cross sectional study Praveen B. Gautam*, Ashwini Mishra, Santosh Kumar INTRODUCTION Tuberculosis is a major public health problem. India accounts for one fourth of the global TB burden.

Sep , &#;&#;Prevalence and patterns of rifampicin and isoniazid resistance-conferring mutations in Mycobacterium tuberculosis isolates from Uganda PLoS One , ( ) , Article e , /journal.pone

Abstract. Tuberculosis (TB) remains a global health problem. The increasing prevalence of drug-resistant Mycobacterium tuberculosis, the causative agent of TB, demands new measures to combat the situation.Rapid and accurate diagnosis of the pathogen and its drug susceptibility pattern is essential for timely initiation of optimal treatment, and, ultimately, control of the disease.

Apr , &#;&#;Prevalence of tuerculosis and rifampicin resistance among patients seeking medical care in Nasarawa State, North central, Nigeria. DOI: /j.sjph Peter Ogie Ikuabe, Ikenna Desmond Ebuenyi. Prevalence of rifampicin resistance by automated Genexpert rifampicin assay in patients with pulmonary tuberculosis in Yenagoa, Nigeria.

Feb , &#;&#;Among previously untreated cases, the prevalence of resistance to isoniazid, rifampicin, ethambutol, and streptomycin was %, %, %, and %, respectively, while prevalence of multidrug resistance (resistance to at least isoniazid and rifampicin) and polyresistance (resistance to two or more drugs, but not both isoniazid and rifampicin ...

The resistant pattern of -bp regions of rpoB gene by Genotype MTBDRplus assay was illutrated in Fig. . The total resistance to rifampicin was % (n = ) and Table shows the resistance profile of M. tuberculosis isolates. Of the M. tuberculosis isolates, % () and % () were from male and female patients, respectively.

Jul , &#;&#;Introduction. Tuberculosis (TB), which is caused by infection with Mycobacterium tuberculosis (MTB) complex, remains a major public health concern worldwide. The emergence of drug-resistant TB, especially rifampicin (RIF)- and multidrug-resistant TB, has greatly impeded progress toward controlling this disease. An estimated million people developed active TB in , of

the prevalence of TB and rifampicin-resistant Mycobacterium tuberculosis (RR-MTB) among presumptive tuberculosis patients using Xpert MTB/RIF assay in Eastern Amhara, Ethiopia. Methods: A retrospective cross-sectional study was conducted among presumptive TB patients from three governmental hospitals in Amhara Regional State. Records of sputum ...

Background: Rapid detection of rifampicin resistance is essential for early management and prevention of transmission of multidrug-resistant tuberculosis (MDR-TB). We studied the prevalence of rifampicin resistance of Mycobacterium tuberculosis (MTB) among

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